A history of second hand smoke exposure: are we asking the right questions?

A history of second hand smoke exposure: are we asking the right questions?

This commentary is written to accompany a special research topic, Second Hand Smoke and COPD: lessons from animal studies, hosted by Frontiers in Respiratory Physiology. Model systems allow researchers to study disease, to tease out cause and effect and mechanisms of action, and to conduct the preliminary studies of the safety and efficacy of treatments. The underlying objective of the research...

Interaction and exposure modification: are we asking the right questions?

Most diseases arise not purely through genetic abnormalities nor purely through environmental causes, but as "complex" conditions brought about by the combined effects of genetic susceptibility factors, nongenetic experiences and exposures, and bad luck. Finding simple models capable of both characterizing such joint effects and providing new insight into pathogenesis remains an ongoing challen...

Are we asking the right questions?

Are We Asking the Right Questions?

Questions about computers replacing teachers sound a lot like the old class size issue. Some wonder if online learning is too focused on drilling fundamentals rather than exploring concepts. Budget issues now involve expensive technology replacing other costs or whether we even need textbooks. And we fully expect a news story soon about whether kindergarten is too early to introduce students to...

Are We Asking All the Right Questions About Quality of Care in Low- and Middle-Income Countries?